Randomized trial of targeted performance feedback to facilitate quality improvement in acute myocardial infarction care

Karen P. Alexander, Tracy Y. Wang, Shuang Li, Barbara L. Lytle, Lara E. Slattery, Sarah Calhoun, Jennifer Poteat, Matthew T. Roe, John S. Rumsfeld, Christopher P. Cannon, Eric D. Peterson

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Background-Efforts to improve quality of care for patients with acute myocardial infarction (AMI) are a national priority. To date, there have been few studies that have prospectively evaluated hospital quality improvement (QI) interventions. Methods and Results-Using hospitals in the National Cardiovascular Data Registry (NCDR) ACTION Registry-GWTG, a cluster randomized trial of the effectiveness of targeted performance feedback to facilitate process improvement for AMI care will be conducted. ACTION Registry-GWTG hospitals with a minimum of 50 AMI patients per 2 quarters are eligible for randomization. The control arm receives standard performance feedback reports, and the intervention arm receives standard performance feedback reports in addition to a supplemental report on the "top 3" centrally identified, hospital-specific performance gaps. The primary outcome will be improvement in a composite of all metrics, and the secondary outcome will be improvement in the targeted metrics. At study inception in January 2009, 149 sites were randomized: 76 to the intervention arm, and 73 to the control arm. Intervention and control sites were well balanced in terms of baseline performance, center characteristics, and AMI volume (-70 patients per quarter). The intervention phase will continue for 5 feedback cycles, each containing 2 quarters of data feedback over 18 months. A final trial outcome report will follow. Conclusions-This randomized trial will evaluate a novel hospital-level QI intervention of targeted performance feedback for AMI, thereby demonstrating the effective use of national registries for QI and furthering our understanding of effective QI methods. Clinical Trial Registration-URL: http://www. clinicaltrials.gov. Unique identifier: NCT00952250. (Circ Cardiovasc Qual Outcomes. 2011;4:129-135.).

Original languageEnglish (US)
Pages (from-to)129-135
Number of pages7
JournalCirculation: Cardiovascular Quality and Outcomes
Issue number1
StatePublished - Jan 2011
Externally publishedYes


  • Randomized controlled trials-quality improvement-acute myocardial infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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