Randomized clinical trials in stroke research

Chul Ahn, Daniel Ahn

Research output: Contribution to journalShort surveypeer-review

11 Scopus citations


A randomized clinical trial is widely regarded as the mostrigorous study design to determine the efficacy of intervention becausespurious causality and bias associated with other experimental designscan be avoided. The purpose of this article is to provide clinicians andclinical researchers the types of randomized clinical trials used in strokestudies and to discuss the advantages and the limitations for each type ofrandomized stroke clinical trials.

Original languageEnglish (US)
Pages (from-to)277-281
Number of pages5
JournalJournal of Investigative Medicine
Issue number2
StatePublished - Feb 2010


  • Advantages
  • Disadvantages
  • RCT

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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