Racial and ethnic disparities in a national cohort of ampullary cancer patients

Ibrahim Nassour, Ali A. Mokdad, Rebecca M. Minter, Patricio M. Polanco, Mathew M. Augustine, John C. Mansour, Matthew R. Porembka, Sam C. Wang

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Background and Objectives: Racial and ethnic variations have been described in the different malignancies, but no such data exists for ampullary cancer. The aim of this study was to present an updated report on the epidemiology, treatment patterns, and survival of a national cohort of ampullary cancer patients. Methods: Patients diagnosed with ampullary cancer between 2004 and 2014 were identified in the National Cancer Database. Overall survival was estimated and compared between racial/ethnic groups using the log-rank test. Results: A total of 14 879 patients were identified; 78% of the patients were White, 9% Hispanic, 8% Black, and 5% Asian. We noted significant differences in disease presentation, socioeconomic status, and outcomes. Blacks had the lowest median overall survival at 18.9 months followed by Whites at 23.9 months, Hispanics at 32.7 months, and Asians at 37.4 months. On a multivariate Cox proportional-hazards model, being Black was associated with worse survival compared to being White while being Asian and Hispanic were associated with better survival. Conclusions: Overall survival of ampullary cancer patients was independently associated with race and ethnicity. Further studies are needed to clarify whether these disparities are primarily due to socioeconomic status or biologic factors.

Original languageEnglish (US)
Pages (from-to)220-227
Number of pages8
JournalJournal of Surgical Oncology
Issue number2
StatePublished - Feb 1 2018


  • ampullary cancer
  • ampullary carcinoma
  • disparity
  • ethnicity
  • race

ASJC Scopus subject areas

  • Surgery
  • Oncology


Dive into the research topics of 'Racial and ethnic disparities in a national cohort of ampullary cancer patients'. Together they form a unique fingerprint.

Cite this