TY - JOUR
T1 - Quantitation of cardiac output with velocity-encoded, phase-difference magnetic resonance imaging
AU - Gregory Hundley, W.
AU - Li, Hong F.
AU - David Hillis, L.
AU - Meshack, Benjamin M.
AU - Lange, Richard A.
AU - Willard, John E.
AU - Landau, Charles
AU - Peshock, Ronald M
N1 - Funding Information:
From the Departments of Internal Medicine (Cardiovascular Division) and Radiology, University of Texas Southwestern Medical Center, Dallas, Texas. Supported in part by National Institutes of Health Spe cial Center of Research grant (Ischemic SCOR grant H1-17669), Bethesda, Maryland, ihe Moss Heart Fund, Dallas, Texas, and grants from the Society of Cardiac Angiography and Intervention (Breckin-rid e, Colorado], Squibb Diagnostics (Princeton, New Jersey), and Picker International, Inc. [Highland Heighk, Ohio). Manuscript received November 16, 1994; revised manuscript received and accepted April 5, 1995.
PY - 1995/6/15
Y1 - 1995/6/15
N2 - Velocity-encoded, phase-difference magnetic resonance imaging (MRI) previously has been used to measure flow in the aorta, as well as in the pulmonary, carotid, and renal arteries, but these measurements have not been validated against currently accepted invasive techniques. To determine the accuracy of velocity-encoded, phase-difference MRI measurements of cardiac output, 23 subjects (11 men and 12 women, aged 15 to 72 years) underwent velocity-encoded, phase-difference MRI measurements of cardiac output in the proximal aorta, followed immediately by cardiac catheterization, with measurement of cardiac output by the Fick principle and by thermodilution. For MRI, Fick, and thermodilution measurements, stroke volume was calculated by dividing cardiac output by heart rate. The magnetic resonance images were acquired in 1 to 3 minutes. For all patients, the agreement between measurements of stroke volume was 3 ± 9 ml for MRI and Fick, -3 ± 11 ml for MRI and thermodilution, and 0 ±8 ml for MRI and the average of Fick and thermodilution. Compared with standard invasive measurements, velocity-encoded, phase-difference MRI can accurately and rapidly determine cardiac output.
AB - Velocity-encoded, phase-difference magnetic resonance imaging (MRI) previously has been used to measure flow in the aorta, as well as in the pulmonary, carotid, and renal arteries, but these measurements have not been validated against currently accepted invasive techniques. To determine the accuracy of velocity-encoded, phase-difference MRI measurements of cardiac output, 23 subjects (11 men and 12 women, aged 15 to 72 years) underwent velocity-encoded, phase-difference MRI measurements of cardiac output in the proximal aorta, followed immediately by cardiac catheterization, with measurement of cardiac output by the Fick principle and by thermodilution. For MRI, Fick, and thermodilution measurements, stroke volume was calculated by dividing cardiac output by heart rate. The magnetic resonance images were acquired in 1 to 3 minutes. For all patients, the agreement between measurements of stroke volume was 3 ± 9 ml for MRI and Fick, -3 ± 11 ml for MRI and thermodilution, and 0 ±8 ml for MRI and the average of Fick and thermodilution. Compared with standard invasive measurements, velocity-encoded, phase-difference MRI can accurately and rapidly determine cardiac output.
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U2 - 10.1016/S0002-9149(99)80772-3
DO - 10.1016/S0002-9149(99)80772-3
M3 - Article
C2 - 7778549
AN - SCOPUS:0029019624
SN - 0002-9149
VL - 75
SP - 1250
EP - 1255
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 17
ER -