Abstract
Human life expectancy is increasing on a global scale, but healthspan—the period of life free from age-associated ill health—is not improving at a comparable rate. This disconnect means that a greater proportion of the general population will spend a longer period of their life suffering from one or more debilitating age-associated diseases, such as cardiovascular disease, Alzheimer's disease, osteoporosis, sarcopenia and various cancers. Understanding the processes underlying ageing and age-related diseases is therefore a major and pressing research challenge in biomedical research.
Original language | English (US) |
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Article number | e100862 |
Journal | EMBO Journal |
Volume | 37 |
Issue number | 22 |
DOIs |
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State | Published - Nov 15 2018 |
Externally published | Yes |
ASJC Scopus subject areas
- Neuroscience(all)
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)