Purified NPC1 protein: I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein

Medicine & Life Sciences

• cholesterol-binding protein 100%
• Niemann-Pick C1 Protein 96%
• oxysterol binding protein 93%
• 25-hydroxycholesterol 54%
• Membrane Proteins 46%
• Oxysterols 40%
• Amino Acids 39%
• Cholesterol 15%
• Hydroxyl Radical 15%
• Sterol Regulatory Element Binding Proteins 10%
• Sterol O-Acyltransferase 10%
• Nonidet P-40 10%
• lipoprotein cholesterol 8%
• Lysosomes 7%
• Protein Binding 6%
• Endoplasmic Reticulum 6%
• Mass Spectrometry 6%
• Carrier Proteins 5%
• Fibroblasts 5%
• Rabbits 4%
• Lipids 4%
• Membranes 4%
• Liver 3%
• In Vitro Techniques 3%

Chemical Compounds

• Oxysterol 86%
• Cholesterol 49%
• 25-Hydroxycholesterol 33%
• Protein 23%
• Acid 19%
• Nonidet P-40 8%
• Acyl-CoA 6%
• Sterol 5%