Pullularia Corneal Ulcer

A patient sustained a corneal abrasion from organic material, used an antibioticcorticosteroid ointment, and developed a corneal ulcer. The common contaminant Pullularia pullulans was isolated from corneal scrapings on two separate occasions. Topical amphotericin B application was ineffective despite in vitro sensitivity. The ulcer was improved by topical application of natamycin (pimaricine) but ultimately required a conjunctival flap for control.