Pulling a MAST1 on Cisplatin Resistance

Ankita B. Jaykumar; Aroon S. Karra; Melanie H. Cobb

doi:10.1016/j.ccell.2018.07.010

Pulling a MAST1 on Cisplatin Resistance

Ankita B. Jaykumar, Aroon S. Karra, Melanie H. Cobb

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death. In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death.

Original language	English (US)
Pages (from-to)	183-185
Number of pages	3
Journal	Cancer Cell
Volume	34
Issue number	2
DOIs	https://doi.org/10.1016/j.ccell.2018.07.010
State	Published - Aug 13 2018

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccell.2018.07.010

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title = "Pulling a MAST1 on Cisplatin Resistance",

abstract = "In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death. In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death.",

author = "Jaykumar, {Ankita B.} and Karra, {Aroon S.} and Cobb, {Melanie H.}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2018",

month = aug,

day = "13",

doi = "10.1016/j.ccell.2018.07.010",

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T1 - Pulling a MAST1 on Cisplatin Resistance

AU - Jaykumar, Ankita B.

AU - Karra, Aroon S.

AU - Cobb, Melanie H.

PY - 2018/8/13

Y1 - 2018/8/13

N2 - In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death. In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death.

AB - In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death. In this issue of Cancer Cell, Jin and colleagues use a kinome-wide screen to identify MAST1 as a cause of cisplatin resistance. They demonstrate that this kinase is a novel activator of MEK1 and the MAPK cascade and that it can harness pathway output to block cisplatin-induced cell death.

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DO - 10.1016/j.ccell.2018.07.010

M3 - Short survey

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VL - 34

SP - 183

EP - 185

JO - Cancer Cell

JF - Cancer Cell

IS - 2

ER -

Pulling a MAST1 on Cisplatin Resistance

Abstract

ASJC Scopus subject areas

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