Psychological challenges and psychiatric illness in earlier stages of CKD

L. Parker Gregg, S. Susan Hedayati

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Patients in the earlier stages of CKD have higher rates of psychological challenges and psychiatric illness than the general population. These challenges may contribute to lower perceived quality of life and progressive kidney disease in such patients. This chapter reviews the mental health literature regarding nondialysis dependent CKD patients. Screening, diagnosis and treatment strategies are discussed for major depression, bipolar depression, anxiety, alcohol use disorder and opioid use disorder. Much of the treatment guidelines are extrapolated from general medical populations. Therefore studies uniquely addressing patients with earlier stages of CKD are needed.

Original languageEnglish (US)
Title of host publicationPsychosocial Aspects of Chronic Kidney Disease
Subtitle of host publicationExploring the Impact of CKD, Dialysis, and Transplantation on Patients
Number of pages26
ISBN (Electronic)9780128170809
ISBN (Print)9780128170816
StatePublished - Jan 1 2020


  • Anxiety
  • Depression
  • Pharmacokinetics
  • Psychiatric disorders
  • Psychopharmacology
  • Substance use

ASJC Scopus subject areas

  • Psychology(all)


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