Psychologic and neurologic function following treatment for childhood temporal lobe astrocytoma

R. K. Mulhern, E. H. Kovnar, L. E. Kun, J. J. Crisco, J. M. Williams

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Seven school-aged children treated for temporal lobe astrocytomas with surgical resection and irradiation were prospectively tested to evaluate their intellectual, academic, personality, and neurologic status after therapy. At their most recent follow-up examination, neuropsychologic functioning was adequate in only two patients. The other five children manifested either intellectual deterioration, learning disability, mental retardation, or psychopathology. These deficits were associated with poor postoperative performance status, inadequate seizure control, tumor recurrence, and younger age at diagnosis. No pattern of intellectual, academic, or personality dysfunction emerged in association with left- versus right-hemisphere tumors.

Original languageEnglish (US)
Pages (from-to)47-52
Number of pages6
JournalJournal of child neurology
Issue number1
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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