PsEma--a hitherto unnamed dermatologic entity with clinical features of both psoriasis and eczema.

William Abramovits, Clay Cockerell, Lisa C. Stevenson, Adrian M. Goldstein, Torsten Ehrig, Alan Menter

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

INTRODUCTION: Recent advances in molecular biology have helped establish differences between psoriasis and a group of inflammatory skin disorders commonly referred to as eczema. The authors have observed significant overlap between these two conditions such that a distinction between them may not always be made, even with histologic examination of skin biopsy specimens. OBJECTIVE: To determine how frequently psoriasis patients present features of both psoriasis and eczema. METHODS: The authors conducted a prospective analysis of 100 consecutive psoriasis patients in their clinic. RESULTS: The authors found that 20% could be diagnosed as "intermediate," having lesions with characteristics of both psoriasis and eczema, or a personal history of both. The authors suggest naming this category of inflammatory dermatosis "PsEma"--an overlap condition in which the clinical, histologic, molecular, biologic, and therapeutic responses show characteristics of both psoriasis and eczema.

Original languageEnglish (US)
Pages (from-to)275-281
Number of pages7
JournalSKINmed
Volume4
Issue number5
DOIs
StatePublished - 2005

ASJC Scopus subject areas

  • Immunology and Allergy
  • Dermatology

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