TY - JOUR
T1 - Protocol paper
T2 - Stepped wedge cluster randomized trial translating the ABCS into optimizing cardiovascular care for people living with HIV
AU - Williams, Stephen K.
AU - Johnson, Brent A.
AU - Tobin, Jonathan N.
AU - Luque, Amneris Esther
AU - Sanders, Mechelle
AU - Carroll, Jennifer K.
AU - Cassells, Andrea
AU - Holder, Tameir
AU - Fiscella, Kevin
N1 - Publisher Copyright:
© 2020
PY - 2020/3/1
Y1 - 2020/3/1
N2 - People living with HIV (PWH) are at higher risk for cardiovascular disease (CVD) and stroke in comparison to their non-infected counterparts. The ABCS (aspirin-blood pressure control-cholesterol control-smoking cessation) reduce atherosclerotic (ASCVD) risk in the general population, but little is known regarding strategies for promoting the ABCS among PWH. Guided by the Consolidated Framework for Implementation Research (CFIR), we designed multilevel implementation strategies that target PWH and their clinicians to promote appropriate use of the ABCS based on a 10-year estimated ASCVD risk. Implementation strategies include patient coaching, automated texting, peer phone support, academic detailing and audit and feedback for the patient's clinician. We are evaluating implementation through a stepped wedge cluster randomized trial based on the Reach-Effectiveness-Adoption-Maintenance/Qualitative-Evaluation-for-Systematic-Translation (RE-AIM/QuEST) mixed methods framework that integrates quantitative and qualitative assessments. The primary outcome is change in ASCVD risk. Findings will have important implications regarding strategies for reducing ASCVD risk among PWH.
AB - People living with HIV (PWH) are at higher risk for cardiovascular disease (CVD) and stroke in comparison to their non-infected counterparts. The ABCS (aspirin-blood pressure control-cholesterol control-smoking cessation) reduce atherosclerotic (ASCVD) risk in the general population, but little is known regarding strategies for promoting the ABCS among PWH. Guided by the Consolidated Framework for Implementation Research (CFIR), we designed multilevel implementation strategies that target PWH and their clinicians to promote appropriate use of the ABCS based on a 10-year estimated ASCVD risk. Implementation strategies include patient coaching, automated texting, peer phone support, academic detailing and audit and feedback for the patient's clinician. We are evaluating implementation through a stepped wedge cluster randomized trial based on the Reach-Effectiveness-Adoption-Maintenance/Qualitative-Evaluation-for-Systematic-Translation (RE-AIM/QuEST) mixed methods framework that integrates quantitative and qualitative assessments. The primary outcome is change in ASCVD risk. Findings will have important implications regarding strategies for reducing ASCVD risk among PWH.
KW - Cardiovascular disease
KW - HIV
KW - Implementation effectiveness
KW - Primary prevention
KW - Risk factors
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U2 - 10.1016/j.pcad.2020.02.003
DO - 10.1016/j.pcad.2020.02.003
M3 - Review article
C2 - 32035124
AN - SCOPUS:85082828505
SN - 0033-0620
VL - 63
SP - 125
EP - 133
JO - Progress in Cardiovascular Diseases
JF - Progress in Cardiovascular Diseases
IS - 2
ER -