Primary hyperparathyroidism in patients with renal stones

J. D. Sedlack, J. Kenkel, B. J R Czarapata, M. G. Paul, J. J. Pahira, T. C. Lee

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


There has been an observed decline in the incidence of renal stones in patients with primary hyperparathyroidism. Some believe that this is related to earlier surgical intervention. Two studies from the 1950s examined the reverse questions to determine the prevalence of primary hyperparathyroidism in patients with renal stones. This report examined 1,500 consecutive patients treated by lithotripsy seen at the Georgetown University Medical Center and found, using the historical criterion for diagnosis of hyperparathryoidism (a serum calcium level of 10.5 miligrams per deciliter or greater) that the prevalence had decreased significantly from 8.0 per cent to our level of 3.02 per cent. Neither age nor sex contributed significantly to this decrease, and there were significantly more calcium stones than in the previous studies. Using an elevated calcium level with an elevated chloride to phosphate ratio as criteria for a diagnosis of probable primary hyperparathyroidism, a true prevalence of 1.65 per cent (± 0.6 per cent) was found. We believe that there has been a significant decrease in the frequency of primary hyperparathryoidism in the general population of patients with renal stones.

Original languageEnglish (US)
Pages (from-to)206-208
Number of pages3
JournalSurgery Gynecology and Obstetrics
Issue number3
StatePublished - 1990

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology


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