Prevention of invasive group A streptococcal disease among household contacts of case patients and among postpartum and postsurgical patients: Recommendations from the centers for disease control and prevention

Matthew R. Moore, Bernard Beall, John Besser, Alan Bisno, Ilin Chuang, Allen S. Craig, Richard Facklam, Janice Fetter, Michael A. Gerber, Gregory Gray, Harry Hill, Lisa Lepine, Orin Levine, Allison McGeer, Michele Pearson, Katherine O'Brien, Anne Schuchat, Mack Sewell, Stanford Shulman, Jane SiegelDennis L. Stevens, Larry Strausbaugh, Chris Van Beneden

Research output: Contribution to journalArticlepeer-review

130 Scopus citations

Abstract

The Centers for Disease Control and Prevention hosted a workshop to formulate recommendations for the control of invasive group A streptococcal (GAS) disease among household contacts of persons with invasive GAS infections and for responding to postpartum and postsurgical invasive GAS infections. Experts reviewed data on the risk of subsequent invasive GAS infection among household contacts of case patients, the effectiveness of chemoprophylactic regimens for eradicating GAS carriage, and the epidemiology of postpartum and postsurgical GAS infection clusters. For household contacts of index patients, routine screening for and chemoprophylaxis against GAS are not recommended. Providers and public health officials may choose to offer chemoprophylaxis to household contacts who are at an increased risk of sporadic disease or mortality due to GAS. One nosocomial postpartum or postsurgical invasive GAS infection should prompt enhanced surveillance and isolate storage, whereas ≥2 cases caused by the same strain should prompt an epidemiological investigation that includes the culture of specimens from epidemiologically linked health care workers.

Original languageEnglish (US)
Pages (from-to)950-959
Number of pages10
JournalClinical Infectious Diseases
Volume35
Issue number8
DOIs
StatePublished - Oct 15 2002

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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