Abstract
MEta-Server for protein Sequence Analysis (MESSA) is a tool that facilitates widespread protein sequence analysis by gathering structural (local sequence properties and three-dimensional structure) and functional (annotations from SWISS-PROT, Gene Ontology terms, and enzyme classification) predictions for a query protein of interest. MESSA uses multiple well-established tools to offer consensus-based predictions on important aspects of protein sequence analysis. Being freely available for noncommercial users and with a user-friendly interface, MESSA serves as an umbrella platform that overcomes the absence of a comprehensive tool for predictive protein analysis. This article reveals how to access MESSA via the Web and shows how to input a protein sequence to analyze using the MESSA web server. It also includes a detailed explanation of the output from MESSA to aid in better interpretation of results.
Original language | English (US) |
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Article number | e84 |
Journal | Current Protocols in Bioinformatics |
Volume | 67 |
Issue number | 1 |
DOIs | |
State | Published - Sep 2019 |
Keywords
- MESSA
- predictions
- protein sequence
- structure and function
ASJC Scopus subject areas
- Structural Biology
- Biochemistry