Potential Biophysiological Mechanisms Underlying Vocal Demands and Vocal Fatigue

Adrianna C. Shembel, Chaya Nanjundeswaran

Research output: Contribution to journalComment/debatepeer-review

5 Scopus citations


Patients with complaint of vocal fatigue have perceptual, acoustic, and aerodynamic outcomes that are heterogeneous in nature. One reason may be due to different underlying biophysiological mechanisms that lead to these heterogeneous clinical presentations. Five potential mechanisms are proposed: neuromuscular, metabolic, vocal tissue, afferent, and central neural. Analytical frameworks and study designs to study these mechanisms are also addressed. A better understanding of biophysiological mechanisms of vocal fatigue can improve precision of therapeutic approaches. It can also help shift management from symptom-based to etiology-focused approaches for vocal fatigue.

Original languageEnglish (US)
JournalJournal of Voice
StateAccepted/In press - 2022


  • Neuromuscular— Metabolic— Vocal cover— Afferent— and Central nervous system

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Speech and Hearing
  • LPN and LVN


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