Potassium Supplementation of Diuretic Therapy: Pro and Con

Jeen R.e. Haalboom, Albert Struyvenberg, Thomas G. Kelsey, Norman M Kaplan, Richard D. Moore, George D. Webb, Jerome P. Kassirer, John T. Harrington

Research output: Contribution to journalLetterpeer-review

1 Scopus citations


To the Editor: In the March 21 issue Kaplan et al.1 report that in 16 hypertensive patients with diuretic-induced hypokalemia, potassium chloride supplements, 60 mmol per day, increased the mean serum potassium concentration by 0.56 mmol per liter. We have reason to doubt the general validity of this observation. Potassium chloride supplementation in diuretic-induced hypokalemia has been extensively studied. In one of these studies,2 done in six elderly patients, the administration of 48 mmol of slow-release potassium chloride per day did not significantly raise either plasma or total body potassium (measured as 42K). In a study in 18 patients with.

Original languageEnglish (US)
Pages (from-to)1021-1023
Number of pages3
JournalNew England Journal of Medicine
Issue number16
StatePublished - Oct 17 1985

ASJC Scopus subject areas

  • Medicine(all)


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