Potassium homeostasis in chronic kidney disease

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Adaptive increases in renal and gastrointestinal excretion of K+ help to prevent hyperkalemia in patients with CKD as long as the GFR remains > 15-20 mL/min. Once the GFR falls below these values, the impact of factors known to adversely affect K+ homeostasis is significantly magnified. Impaired renal K+ excretion can be the result of conditions that severely limit distal Na+ delivery, decreased mineralocorticoid levels or activity, or a distal tubular defect (Table 2). In clinical practice, hyperkalemia is usually the result of a combination of factors superimposed on renal dysfunction.

Original languageEnglish (US)
JournalNephrology news & issues
Issue number4
StatePublished - Apr 1 2016

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Potassium homeostasis in chronic kidney disease'. Together they form a unique fingerprint.

Cite this