Postradiotherapy surveillance practice for head and neck squamous cell carcinoma - Too much for too little?

David L. Schwartz, Jerry Barker, Kari Chansky, Bevan Yueh, Leila Raminfar, Pamela Drago, Christine Cha, Mary Austin-Seymour, George E. Laramore, Allen D. Hillel, Ernest A. Weymuller, Kent E. Wallner

Research output: Contribution to journalArticlepeer-review

86 Scopus citations


Introduction. Limited information is available regarding surveillance patterns after head and neck cancer radiotherapy. We cataloged follow-up for a specified patient cohort treated at three neighboring university, community, and Veterans Administration institutions. Methods. One hundred fifteen patients were treated with curative intent between 1994-1998 with definitive or postoperative radiotherapy for newly diagnosed squamous cell carcinoma of the oral cavity, oropharynx, larynx, or hypopharynx. One hundred patients had continuous follow-up at their treating institution and were included for analysis. Median follow-up until disease recurrence or censorship was 28.5 months. Results. Median follow-up frequency was 5.7 visits/year and was highly variable. Although visit frequency correlated with disease stage and the presence of high-risk disease features, this association was lost when patients with early recurrences were removed from analysis. Procedure and test utilization closely mirrored visit frequency, resulting in a wide range of estimated yearly charges ($0-15,668/year; median, $1,772/year). Actuarial 3-year overall survival for the study group was 71%. Eighty-six percent (19 of 22) of potentially salvageable locoregional failures were discovered secondary to symptomatic complaint rather than by test results. Disease failure, whether detected by symptom or testing, predicted for poor survival (22% at 24 months after recurrence). Conclusions. Postradiotherapy surveillance for head and neck cancer is inconsistently pursued. A proven correlation between intensive follow-up and improved patient survival is lacking. Surveillance directed by patient symptoms should be investigated as an alternative approach.

Original languageEnglish (US)
Pages (from-to)990-999
Number of pages10
JournalHead and Neck
Issue number12
StatePublished - Dec 2003


  • Cost analysis
  • Follow-up
  • Head and neck cancer
  • Radiotherapy
  • Surveillance

ASJC Scopus subject areas

  • Otorhinolaryngology


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