TY - JOUR
T1 - Positive clinical risk factors predict a high rate of methicillin-resistant Staphylococcus aureus colonization in emergency department patients
AU - Wakatake, Haruaki
AU - Fujitani, Shigeki
AU - Kodama, Takamitsu
AU - Kawamoto, Eiji
AU - Yamada, Hiroyuki
AU - Yanai, MacHi
AU - Morisawa, Kenichiro
AU - Takemura, Hiromu
AU - Lefor, Alan T.
AU - Taira, Yasuhiko
PY - 2012/12
Y1 - 2012/12
N2 - Background: This study was undertaken to determine the rate of methicillin-resistant Staphylococcus aureus (MRSA) colonization predicted by clinical risk factors compared with determination by nasal swab culture and polymerase chain reaction in emergency department patients. Methods: From November 2009 to March 2011, patients seen in the emergency department were studied prospectively. The risk of MRSA colonization was determined by clinical risk factors, and both surveillance cultures and a polymerase chain reaction assay were performed in each patient. Results: A total of 277 patients was enrolled, and 31.4% (87/277) of patients had a positive surveillance culture or a MRSA polymerase chain reaction assay. The rate of colonization in patients with high-risk factors included the following: past history of colonization/infections, 60.0%; history of previous antibiotic use, 47.2%; more than 30 days hospitalization in the past 3 months, 43.9%; more than 10 days hospitalization in the past 3 months, 41.7%; and a history of hospitalization because of acute illness, 40.0%. Conclusion: The prevalence rate of colonization in patients with a high risk of MRSA colonization exceeded 30%. Active surveillance cultures should be considered in patients at high risk for MRSA colonization.
AB - Background: This study was undertaken to determine the rate of methicillin-resistant Staphylococcus aureus (MRSA) colonization predicted by clinical risk factors compared with determination by nasal swab culture and polymerase chain reaction in emergency department patients. Methods: From November 2009 to March 2011, patients seen in the emergency department were studied prospectively. The risk of MRSA colonization was determined by clinical risk factors, and both surveillance cultures and a polymerase chain reaction assay were performed in each patient. Results: A total of 277 patients was enrolled, and 31.4% (87/277) of patients had a positive surveillance culture or a MRSA polymerase chain reaction assay. The rate of colonization in patients with high-risk factors included the following: past history of colonization/infections, 60.0%; history of previous antibiotic use, 47.2%; more than 30 days hospitalization in the past 3 months, 43.9%; more than 10 days hospitalization in the past 3 months, 41.7%; and a history of hospitalization because of acute illness, 40.0%. Conclusion: The prevalence rate of colonization in patients with a high risk of MRSA colonization exceeded 30%. Active surveillance cultures should be considered in patients at high risk for MRSA colonization.
KW - PCR
KW - Polymerase chain reaction
KW - Staphylococcus aureus
UR - http://www.scopus.com/inward/record.url?scp=84870448180&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84870448180&partnerID=8YFLogxK
U2 - 10.1016/j.ajic.2012.01.017
DO - 10.1016/j.ajic.2012.01.017
M3 - Article
C2 - 22627097
AN - SCOPUS:84870448180
SN - 0196-6553
VL - 40
SP - 988
EP - 991
JO - American Journal of Infection Control
JF - American Journal of Infection Control
IS - 10
ER -