Polymorphism of a Qa‐1‐associated antigen defined by cytotoxic T cells. I. Qed‐1^a and Qed‐1^d

Tla^d mice have a distinct Qed‐1 allele, Qed‐1^d. Its product is detected by cytotoxic T cells raised in C57BW6 (H‐2^b, Tla^b) mice against cells from a new recombinant, B6‐TL.123⁺ (H‐2^b, Tla^d/b). Qed‐1^d is also found on cells from B10.M, A.CA and B10.STC90 mice. It cross‐reacts weakly with Qed‐1^b. (C57BL/6 X BALB/c) F₁ anti‐B10. A (SR) effectors discriminate Qed‐1^a and Qed‐1^d, while C3H/HeJ anti‐B10. BR effectors cross‐react extensively. CB6F₁ anti‐5R effector cells also discriminate between the Qed‐1 antigens of B6‐Tla^a (H‐2^b, Tla^a) and those of B10. BR and other H‐2k, Tla^a strains.