TY - JOUR
T1 - Polyarteritis in Children
AU - Reimold, E. W.
AU - Weinberg, A. G.
AU - Fink, C. W.
AU - Battles, N. D.
PY - 1976/5
Y1 - 1976/5
N2 - Polyarteritis was diagnosed in three girls, 9 to 10 years old, by kidney and skin biopsies. They were treated with a combination of prednisone (1.5 to 2 mg/kg) and cyclophosphamide (2 mg/kg) for up to 12 months. The illness was severe in all three, complicated by hypertension, seizures, pulmonary infiltrates, renal failure, or hallucinations. All three patients are alive and well with no or minimal residual symptoms two to three years after therapy was discontinued. The treatment with corticosteroids or with a combination of steroids and immunosuppressive drugs seems to improve the prognosis of polyarteritis considerably.
AB - Polyarteritis was diagnosed in three girls, 9 to 10 years old, by kidney and skin biopsies. They were treated with a combination of prednisone (1.5 to 2 mg/kg) and cyclophosphamide (2 mg/kg) for up to 12 months. The illness was severe in all three, complicated by hypertension, seizures, pulmonary infiltrates, renal failure, or hallucinations. All three patients are alive and well with no or minimal residual symptoms two to three years after therapy was discontinued. The treatment with corticosteroids or with a combination of steroids and immunosuppressive drugs seems to improve the prognosis of polyarteritis considerably.
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U2 - 10.1001/archpedi.1976.02120060080015
DO - 10.1001/archpedi.1976.02120060080015
M3 - Article
C2 - 5883
AN - SCOPUS:0017034498
SN - 2168-6203
VL - 130
SP - 534
EP - 541
JO - A.M.A. American journal of diseases of children
JF - A.M.A. American journal of diseases of children
IS - 5
ER -