Platelet activity and outcome after intracerebral hemorrhage

Andrew M. Naidech; Richard A. Bernstein; Kimberly Levasseur; Sarice L. Bassin; Bernard R. Bendok; H. Hunt Batjer; Thomas P. Bleck; Mark J. Alberts

doi:10.1002/ana.21618

Platelet activity and outcome after intracerebral hemorrhage

Andrew M. Naidech, Richard A. Bernstein, Kimberly Levasseur, Sarice L. Bassin, Bernard R. Bendok, H. Hunt Batjer, Thomas P. Bleck, Mark J. Alberts

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65 Scopus citations

Abstract

There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.

Original language	English (US)
Pages (from-to)	352-356
Number of pages	5
Journal	Annals of Neurology
Volume	65
Issue number	3
DOIs	https://doi.org/10.1002/ana.21618
State	Published - Mar 1 2009

ASJC Scopus subject areas

Neurology
Clinical Neurology

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abstract = "There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.",

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AU - Naidech, Andrew M.

AU - Bernstein, Richard A.

AU - Levasseur, Kimberly

AU - Bassin, Sarice L.

AU - Bendok, Bernard R.

AU - Batjer, H. Hunt

AU - Bleck, Thomas P.

AU - Alberts, Mark J.

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AB - There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.

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Platelet activity and outcome after intracerebral hemorrhage

Abstract

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