Physostigmine reversal of postoperative somnolence

Gary E. Hill; Theodore H. Stanley; Craig R. Sentker

doi:10.1007/BF03006714

Physostigmine reversal of postoperative somnolence

Gary E. Hill, Theodore H. Stanley, Craig R. Sentker

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

The effects of physostigmine on reversal of post-operative somnolence following general anaesthesia were evaluated in 187 patients. Significant reversal of anaesthetic-induced post-operative somnolence was observed in those patients receiving physostigmine when compared to a control group. These results suggest that general anaesthesia with halothane may be included in those situations where central nervous system depression may be reversed by administration of physostigmine. Cholinergic side-effects observed with physostigmine administration were minimal.

Original language	English (US)
Pages (from-to)	707-711
Number of pages	5
Journal	Canadian Anaesthetists' Society Journal
Volume	24
Issue number	6
DOIs	https://doi.org/10.1007/BF03006714
State	Published - Nov 1977

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1007/BF03006714

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abstract = "The effects of physostigmine on reversal of post-operative somnolence following general anaesthesia were evaluated in 187 patients. Significant reversal of anaesthetic-induced post-operative somnolence was observed in those patients receiving physostigmine when compared to a control group. These results suggest that general anaesthesia with halothane may be included in those situations where central nervous system depression may be reversed by administration of physostigmine. Cholinergic side-effects observed with physostigmine administration were minimal.",

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year = "1977",

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AU - Stanley, Theodore H.

AU - Sentker, Craig R.

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AB - The effects of physostigmine on reversal of post-operative somnolence following general anaesthesia were evaluated in 187 patients. Significant reversal of anaesthetic-induced post-operative somnolence was observed in those patients receiving physostigmine when compared to a control group. These results suggest that general anaesthesia with halothane may be included in those situations where central nervous system depression may be reversed by administration of physostigmine. Cholinergic side-effects observed with physostigmine administration were minimal.

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Physostigmine reversal of postoperative somnolence

Abstract

ASJC Scopus subject areas

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