Physostigmine reversal of postoperative somnolence

Gary E. Hill, Theodore H. Stanley, Craig R. Sentker

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The effects of physostigmine on reversal of post-operative somnolence following general anaesthesia were evaluated in 187 patients. Significant reversal of anaesthetic-induced post-operative somnolence was observed in those patients receiving physostigmine when compared to a control group. These results suggest that general anaesthesia with halothane may be included in those situations where central nervous system depression may be reversed by administration of physostigmine. Cholinergic side-effects observed with physostigmine administration were minimal.

Original languageEnglish (US)
Pages (from-to)707-711
Number of pages5
JournalCanadian Anaesthetists' Society Journal
Issue number6
StatePublished - Nov 1977

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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