Physics and biology of transcutaneous bilirubin assay

Daniele De Luca, Anton V. Malko, Ricardo Moreno Alonso de Celada, Raul de Lucas Laguna, William D. Engle

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Obtaining a transcutaneous bilirubin (TcB) measurement is a rather simple and straightforward process that is carried out thousands of times each day in hospitals and in other medical settings throughout the world. However, the physics and biology behind TcB measurements are actually rather complex. The purpose of this chapter is to briefly review the optical properties of human skin and subcutaneous tissue and to explain the biochemistry of bilirubin in the skin. An understanding of these topics is necessary in order to appreciate how transcutaneous bilirubinometry works and how it provides the clinical information that is used routinely.

Original languageEnglish (US)
Title of host publicationTranscutaneous Bilirubinometry
PublisherNova Science Publishers, Inc.
Number of pages14
ISBN (Print)9781626182486
StatePublished - Mar 2013

ASJC Scopus subject areas

  • Medicine(all)


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