Photoimmunology-illuminating the immune system through photobiology

Justin Leitenberger; Heidi Jacobe; Ponciano D Cruz

doi:10.1007/s00281-007-0063-6

Photoimmunology-illuminating the immune system through photobiology

Justin Leitenberger, Heidi Jacobe, Ponciano D Cruz

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Abstract

We review the field of photoimmunology with emphasis on immunosuppression induced by ultraviolet B radiation. Recent studies have focused on UVB-induced alterations in epidermal Langerhans cell function, resulting in a shift from Th1 to Th2 phenotype and the activation of regulatory T cells as the source of IL-10 that is central to this form of immunosuppression.

Original language	English (US)
Pages (from-to)	65-70
Number of pages	6
Journal	Seminars in Immunopathology
Volume	29
Issue number	1
DOIs	https://doi.org/10.1007/s00281-007-0063-6
State	Published - Apr 1 2007

Keywords

Antigen-presenting cells
Cytokines
Immunosuppression
Regulatory T cells
Ultraviolet radiation

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1007/s00281-007-0063-6

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abstract = "We review the field of photoimmunology with emphasis on immunosuppression induced by ultraviolet B radiation. Recent studies have focused on UVB-induced alterations in epidermal Langerhans cell function, resulting in a shift from Th1 to Th2 phenotype and the activation of regulatory T cells as the source of IL-10 that is central to this form of immunosuppression.",

keywords = "Antigen-presenting cells, Cytokines, Immunosuppression, Regulatory T cells, Ultraviolet radiation",

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AB - We review the field of photoimmunology with emphasis on immunosuppression induced by ultraviolet B radiation. Recent studies have focused on UVB-induced alterations in epidermal Langerhans cell function, resulting in a shift from Th1 to Th2 phenotype and the activation of regulatory T cells as the source of IL-10 that is central to this form of immunosuppression.

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KW - Immunosuppression

KW - Regulatory T cells

KW - Ultraviolet radiation

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Photoimmunology-illuminating the immune system through photobiology

Abstract

Keywords

ASJC Scopus subject areas

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