Phagocytosis of yeast by human oocytes: Fine structural observations

J. K. Koehler, W. R. Smith, S. Ravnik

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Fine‐structure observations have been made on the interaction between invasive yeast cells and human oocytes. The yeast appear to make their way through the zona pellucida and once in the perivitelline space are incorporated into phagocytic vacuoles by surface activity of the oocyte. The yeast attach to the vitelline membrane via fuzzy surface material on the cell wall, and incorporation appears to be aided by oocyte microvillar activity. Coated pits in the oocyte plasma membrane are incorporated into the phagosomes, but no lysosomal activity is seen, and neither oocytes nor yeast cels appear to undergo degeneration in the time frame investigated.

Original languageEnglish (US)
Pages (from-to)237-244
Number of pages8
JournalGamete Research
Issue number3
StatePublished - Jul 1987


  • Candida albicans
  • electron microscopy
  • phagosomes

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology


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