Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia

Kelly K. Park, Bailey Tayebi, Lily Uihlein, Jodi Speiser, Adnan Mir, Pedram Gerami, Anthony Mancini, Wendy Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.

Original languageEnglish (US)
Pages (from-to)e74-e75
JournalPediatric Dermatology
Issue number1
StatePublished - Jan 1 2018


  • acute lymphoblastic leukemia
  • chilblains
  • leukemia cutis
  • pernio

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology


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