TY - JOUR
T1 - Peripheral corneal disorders
AU - Robin, Jeffrey B.
AU - Schanzlin, David J.
AU - Verity, Steven
AU - Barron, Bruce A.
AU - Arffa, Robert C.
AU - Suarez, Enrique
AU - Kaufman, Herbert E.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1986
Y1 - 1986
N2 - The peripheral cornea is anatomically and physiologically distinct from its central counterpart. The major differences relate to the gradual transition of corneal tissues to those of the conjunctiva, episclera, and sclera; furthermore, the vascular structures, lymphatics, and inflammatory cells from these neighboring structures are intimately associated with the limbus and periphery of the cornea. The peripheral cornea is thereby predisposed to three main classes of disorders which do not normally involve the central cornea. First, local conditions affecting the sclera and conjunctiva may secondarily spread to involve the limbus and peripheral cornea. These include several infectious diseases, as well as hypersensitivity conditions, mass lesions, and degenerations. Second, due to the associated blood vessels and lymphatics, the peripheral cornea may be involved in a variety of systemic diseases, including vasculitides, autoimmune disorders, and abnormal metabolic conditions. Finally, there are several conditions, such as the noninflammatory peripheral degenerations, which primarily affect the peripheral cornea without associated ocular or systemic changes. In this review, we present a classification and discussion of the various disorders which may involve the peripheral cornea.
AB - The peripheral cornea is anatomically and physiologically distinct from its central counterpart. The major differences relate to the gradual transition of corneal tissues to those of the conjunctiva, episclera, and sclera; furthermore, the vascular structures, lymphatics, and inflammatory cells from these neighboring structures are intimately associated with the limbus and periphery of the cornea. The peripheral cornea is thereby predisposed to three main classes of disorders which do not normally involve the central cornea. First, local conditions affecting the sclera and conjunctiva may secondarily spread to involve the limbus and peripheral cornea. These include several infectious diseases, as well as hypersensitivity conditions, mass lesions, and degenerations. Second, due to the associated blood vessels and lymphatics, the peripheral cornea may be involved in a variety of systemic diseases, including vasculitides, autoimmune disorders, and abnormal metabolic conditions. Finally, there are several conditions, such as the noninflammatory peripheral degenerations, which primarily affect the peripheral cornea without associated ocular or systemic changes. In this review, we present a classification and discussion of the various disorders which may involve the peripheral cornea.
KW - Mooren's ulcer
KW - Terrien's marginal degeneration
KW - collagen vascular diseases
KW - corneal degenerations
KW - corneal tumors
KW - dellen
KW - infectious keratitis
KW - marginal ulcer
KW - pellucid marginal degeneration
KW - peripheral cornea
KW - phlyctenulosis
KW - rosacea
KW - vernal keratoconjunctivitis
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U2 - 10.1016/0039-6257(86)90049-4
DO - 10.1016/0039-6257(86)90049-4
M3 - Review article
C2 - 3529467
AN - SCOPUS:0022474591
SN - 0039-6257
VL - 31
SP - 1
EP - 36
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
IS - 1
ER -