Abstract
We describe a patient who as a teenager developed a sensory-motor polyneuropathy with optic atrophy. Over the next three decades, multiple cranial neuropathies appeared. Striking areas of subperineurial cellular proliferation were observed on sural nerve biopsy. The ultrastructural and immunohistochemical characteristics of these aggregates were those of perineurial cell hyperplasia. To our knowledge, this is the second full report associating perineurial cell hyperplasia with a sensory-motor polyneuropathy and the first in the English literature. Copyright (C) 2000 Elsevier Science B.V.
Original language | English (US) |
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Pages (from-to) | 503-506 |
Number of pages | 4 |
Journal | Neuromuscular Disorders |
Volume | 10 |
Issue number | 7 |
DOIs | |
State | Published - Oct 2000 |
Keywords
- Cranial neuropathy
- Hyperplasia
- Optic atrophy
- Perineurial cells
- Polyneuropathy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Neurology
- Clinical Neurology
- Genetics(clinical)