Performance evaluation of hydroxylated and acylated silicone rubber coatings

Chi Chun Tsai; Michael L. Dollar; Anca Constantinescu; Padmakar V. Kulkarni; Robert C. Eberhart

Performance evaluation of hydroxylated and acylated silicone rubber coatings

Chi Chun Tsai
, Michael L. Dollar
, Anca Constantinescu
, Padmakar V. Kulkarni
, Robert C. Eberhart

Research output: Contribution to journal › Conference article › peer-review

Abstract

Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced ¹¹¹In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

Original language	English (US)
Pages (from-to)	M192-M193
Journal	ASAIO Transactions
Volume	37
Issue number	3
State	Published - Jul 1991

ASJC Scopus subject areas

Biophysics

Cite this

@article{13fe4767600a41a78659a8300d34a643,

title = "Performance evaluation of hydroxylated and acylated silicone rubber coatings",

abstract = "Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.",

author = "Tsai, \{Chi Chun\} and Dollar, \{Michael L.\} and Anca Constantinescu and Kulkarni, \{Padmakar V.\} and Eberhart, \{Robert C.\}",

year = "1991",

month = jul,

language = "English (US)",

volume = "37",

pages = "M192--M193",

journal = "ASAIO Transactions",

issn = "0889-7190",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - Performance evaluation of hydroxylated and acylated silicone rubber coatings

AU - Tsai, Chi Chun

AU - Dollar, Michael L.

AU - Constantinescu, Anca

AU - Kulkarni, Padmakar V.

AU - Eberhart, Robert C.

PY - 1991/7

Y1 - 1991/7

N2 - Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

AB - Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

UR - https://www.scopus.com/pages/publications/0026193343

UR - https://www.scopus.com/pages/publications/0026193343#tab=citedBy

M3 - Conference article

C2 - 1751105

AN - SCOPUS:0026193343

SN - 0889-7190

VL - 37

SP - M192-M193

JO - ASAIO Transactions

JF - ASAIO Transactions

IS - 3

ER -

Performance evaluation of hydroxylated and acylated silicone rubber coatings

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this