Performance evaluation of hydroxylated and acylated silicone rubber coatings

Chi Chun Tsai; Michael L. Dollar; Anca Constantinescu; Padmakar V. Kulkarni; Robert C. Eberhart

Performance evaluation of hydroxylated and acylated silicone rubber coatings

Chi Chun Tsai, Michael L. Dollar, Anca Constantinescu, Padmakar V. Kulkarni, Robert C. Eberhart

Research output: Contribution to journal › Conference article › peer-review

Abstract

Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced ¹¹¹In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

Original language	English (US)
Pages (from-to)	M192-M193
Journal	ASAIO Transactions
Volume	37
Issue number	3
State	Published - Jul 1991

ASJC Scopus subject areas

Biophysics

Cite this

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title = "Performance evaluation of hydroxylated and acylated silicone rubber coatings",

abstract = "Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.",

author = "Tsai, {Chi Chun} and Dollar, {Michael L.} and Anca Constantinescu and Kulkarni, {Padmakar V.} and Eberhart, {Robert C.}",

year = "1991",

month = jul,

language = "English (US)",

volume = "37",

pages = "M192--M193",

journal = "ASAIO Transactions",

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publisher = "Lippincott Williams and Wilkins",

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T1 - Performance evaluation of hydroxylated and acylated silicone rubber coatings

AU - Tsai, Chi Chun

AU - Dollar, Michael L.

AU - Constantinescu, Anca

AU - Kulkarni, Padmakar V.

AU - Eberhart, Robert C.

PY - 1991/7

Y1 - 1991/7

N2 - Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

AB - Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

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M3 - Conference article

C2 - 1751105

AN - SCOPUS:0026193343

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Performance evaluation of hydroxylated and acylated silicone rubber coatings

Abstract

ASJC Scopus subject areas

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