Pediatric multiple sclerosis: What we know and where are we headed?

William S. MacAllister, Christopher Christodoulou, Maria Milazzo, Thomas E. Preston, Dana Serafin, Lauren B. Krupp, Lana Harder

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Multiple Sclerosis (MS), an autoimmune mediated disease of the central nervous system, has historically been considered a disease of young adulthood. However, there has been increasing recognition that the disease can occur in adolescence and even early childhood and recent years have witnessed a surge of studies documenting the clinical features of the disease as it pertains to this young population. The purpose of this article is to review the literature on MS in childhood and adolescence, including the clinical presentation of the disease in this group, neuropathology and pathogenesis, magnetic resonance imaging findings, as well as neuropsychological and psychosocial considerations.

Original languageEnglish (US)
Pages (from-to)1-22
Number of pages22
JournalChild Neuropsychology
Issue number1
StatePublished - Jan 30 2013


  • Childhood
  • Fatigue
  • Multiple Sclerosis
  • Neuropsychological
  • Treatment.

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology


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