Palladium-catalyzed cross-benzannulation of aminoenynes with diynes. Highly regioselective synthesis of polysubstituted anilines

Shinichi Saito; Naoyuki Uchiyama; Vladimir Gevorgyan; Yoshinori Yamamoto

doi:10.1021/jo000171m

Palladium-catalyzed cross-benzannulation of aminoenynes with diynes. Highly regioselective synthesis of polysubstituted anilines

Shinichi Saito, Naoyuki Uchiyama, Vladimir Gevorgyan, Yoshinori Yamamoto

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Polysubstituted anilines were prepared by the palladium-catalyzed cross- benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.

Original language	English (US)
Pages (from-to)	4338-4341
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	65
Issue number	14
DOIs	https://doi.org/10.1021/jo000171m
State	Published - Jul 14 2000
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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abstract = "Polysubstituted anilines were prepared by the palladium-catalyzed cross- benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.",

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T1 - Palladium-catalyzed cross-benzannulation of aminoenynes with diynes. Highly regioselective synthesis of polysubstituted anilines

AU - Saito, Shinichi

AU - Uchiyama, Naoyuki

AU - Gevorgyan, Vladimir

AU - Yamamoto, Yoshinori

PY - 2000/7/14

Y1 - 2000/7/14

N2 - Polysubstituted anilines were prepared by the palladium-catalyzed cross- benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.

AB - Polysubstituted anilines were prepared by the palladium-catalyzed cross- benzannulation of conjugated aminoenynes 1-4 with diynes 8. The reaction proceeded in a highly regioselective manner under mild conditions, and the anilines were obtained as single regioisomers. Our method complements the well-known precedures for the preparation of polysubstituted anilines which are widely used in organic synthesis.

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Palladium-catalyzed cross-benzannulation of aminoenynes with diynes. Highly regioselective synthesis of polysubstituted anilines

Abstract

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