Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety

Medicine & Life Sciences

• Anxiety 60%
• Cocaine 83%
• Cocaine-Related Disorders 8%
• Cyclic AMP Response Element-Binding Protein 8%
• Epigenetic Repression 10%
• Epigenomics 11%
• Foot 5%
• Histones 78%
• Lysine 6%
• Motivation 5%
• Neurons 3%
• Nucleus Accumbens 90%
• Psychology Reinforcement 6%
• Reward 6%
• Self Administration 100%
• Shock 5%