Overexpression of HER2 (erbB2) in human breast epithelial cells unmasks transforming growth factor β-induced cell motility

Medicine & Life Sciences

• human ERBB2 protein 100%
• Transforming Growth Factors 85%
• Cell Movement 66%
• Breast 61%
• Epithelial Cells 58%
• Trastuzumab 24%
• Blocking Antibodies 16%
• Protein Kinase Inhibitors 14%
• rac1 GTP-Binding Protein 10%
• 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 10%
• U 0126 8%
• Stress Fibers 8%
• Pseudopodia 8%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 8%
• Growth Factor Receptors 7%
• p38 Mitogen-Activated Protein Kinases 7%
• Phosphatidylinositol 3-Kinase 6%
• Mitogen-Activated Protein Kinases 6%
• Wounds and Injuries 6%
• Integrins 6%
• Actins 5%
• Ligands 4%
• Cell Proliferation 4%
• Proteins 2%
• Neoplasms 2%

Chemical Compounds

• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 26%
• U0126 15%
• LY294002 14%
• Phosphatidylinositol 3 Kinase Inhibitor 14%
• Antiproliferative 8%
• Fiber 5%
• Protein 3%