Outside in: Inversion of cell polarity controls epithelial lumen formation

George E. Davis, Ondine B. Cleaver

Research output: Contribution to journalShort surveypeer-review

9 Scopus citations


Establishment of cell polarity is important for epithelial lumen formation, and the molecular mechanisms directing this process are only partially understood. In this issue of Developmental Cell, Bryant etal. (2014) show that disassembly, membrane translocation, and reassembly of podocalyxin complexes controls epithelial cell polarization and lumen formation in 3D matrices.

Original languageEnglish (US)
Pages (from-to)140-142
Number of pages3
JournalDevelopmental cell
Issue number2
StatePublished - Oct 27 2014

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology


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