OCT-aided anastomosis platform study in the rodent model

Yong Huang, Dedi Tong, Shan Zhu, Lehao Wu, Zuhaib Ibrahim, Wp Andrew Lee, Gerald Brandacher, Jin U. Kang

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Anastomosis is one of the most commonly performed procedure in the clinical environment that involves tubular structures, such as blood vessel, lymphatic vessel, seminal duct and ureter. Suture based anastomosis is still the foundation for most basic surgical training and clinical operation, although alternate techniques have been developed and under development. For those tubular-structure-anastomosis, immediate real-time post-operative evaluation of the surgical outcome is critical to the success of surgery. Previously evaluation is mostly based on surgeons' experience. Fourier-domain optical coherence tomography is high-speed, high-resolution noninvasive 3D imaging modality that has been widely used in the biomedical research and clinical study. In this study we used Fourier-domain optical coherence tomography as an evaluation tool for anastomosis of lymphatic vessels, ureter and seminal duct in rodent model. Immediate post-operative and long term surgical site data were collected and analyzed. Critical clinical parameters such as lumen patency, anastomosed site narrowing and suture error detection are provided to surgeons.

Original languageEnglish (US)
Title of host publicationAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII
ISBN (Print)9780819498489
StatePublished - 2014
Externally publishedYes
EventAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII - San Francisco, CA, United States
Duration: Feb 2 2014Feb 4 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceAdvanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII
Country/TerritoryUnited States
CitySan Francisco, CA


  • Anastomosis
  • Lymphaticovenous anastomosis
  • Optical coherence tomography
  • Postoperative evaluation
  • Real-time processing
  • Ureteral anastomosis
  • Vasovasostomy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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