Obstructive hydrocephalus and intracerebral mass secondary to Epicoccum nigrum

Research output: Contribution to journalArticlepeer-review


Here we report a case of a 14-week-old girl with a history of intrauterine drug exposure and hypoxic ischemic encephalopathy secondary to cardiac arrest requiring prolonged resuscitation at birth presented with irritability and a bulging anterior fontanelle. After neurosurgical resection, pathologic examination showed fungal hyphae, and Epicoccum nigrum was detected by fungal PCR and sequencing. To our knowledge, this is the first reported case of a central nervous system infection due to Epicoccum nigrum.

Original languageEnglish (US)
Pages (from-to)18-21
Number of pages4
JournalMedical Mycology Case Reports
StatePublished - Mar 2022


  • Epicoccum nigrum
  • Fungal CNS infection
  • Intracerebral fungal mass
  • Obstructive hydrocephalus

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases


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