Novel targeting and activation strategies for photodynamic therapy

Juan Chen; Ian R. Corbin; Gang Zheng

doi:10.1007/978-0-387-71809-5_13

Novel targeting and activation strategies for photodynamic therapy

Juan Chen, Ian R. Corbin, Gang Zheng

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

Original language	English (US)
Title of host publication	Proceedings of Light-Activated Tissue Regeneration and Therapy Conference
Pages	127-147
Number of pages	21
DOIs	https://doi.org/10.1007/978-0-387-71809-5_13
State	Published - 2008
Event	2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007 - Tomar, Portugal Duration: Jun 24 2007 → Jun 29 2007

Publication series

Name	Lecture Notes in Electrical Engineering
Volume	12 LNEE
ISSN (Print)	1876-1100
ISSN (Electronic)	1876-1119

Other

Other	2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007
Country/Territory	Portugal
City	Tomar
Period	6/24/07 → 6/29/07

Keywords

High density lipoproteins
Low density lipoproteins
Lysine residues
Molecular beacons
Nanoparticles
Receptors

ASJC Scopus subject areas

Industrial and Manufacturing Engineering

Access to Document

10.1007/978-0-387-71809-5_13

Cite this

Chen, J, Corbin, IR & Zheng, G 2008, Novel targeting and activation strategies for photodynamic therapy. in Proceedings of Light-Activated Tissue Regeneration and Therapy Conference. Lecture Notes in Electrical Engineering, vol. 12 LNEE, pp. 127-147, 2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007, Tomar, Portugal, 6/24/07. https://doi.org/10.1007/978-0-387-71809-5_13

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title = "Novel targeting and activation strategies for photodynamic therapy",

abstract = "Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.",

keywords = "High density lipoproteins, Low density lipoproteins, Lysine residues, Molecular beacons, Nanoparticles, Receptors",

author = "Juan Chen and Corbin, {Ian R.} and Gang Zheng",

note = "Funding Information: This work was supported by grants from National Institute of Health, Department of Defense and Oncologic Foundation of Buffalo.; 2nd Conference on {"}Light-Activated Tissue Regeneration and Therapy{"} an Engineering Conference International, ECI 2007 ; Conference date: 24-06-2007 Through 29-06-2007",

year = "2008",

doi = "10.1007/978-0-387-71809-5_13",

language = "English (US)",

isbn = "9780387718088",

series = "Lecture Notes in Electrical Engineering",

pages = "127--147",

booktitle = "Proceedings of Light-Activated Tissue Regeneration and Therapy Conference",

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T1 - Novel targeting and activation strategies for photodynamic therapy

AU - Chen, Juan

AU - Corbin, Ian R.

AU - Zheng, Gang

N1 - Funding Information: This work was supported by grants from National Institute of Health, Department of Defense and Oncologic Foundation of Buffalo.

PY - 2008

Y1 - 2008

N2 - Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

AB - Photodynamic treatments can be enhanced by (1) selective, precise delivery, (2) specific delivery of the sensitizer to the cancer tissue, and (3) precise control of the sensitizer's ability to produce singlet oxygen. Fiber optic delivery can assist with light control. This paper focuses on loading sensitizer into low and high density lipoproteins and using nanoparticles into specific receptors for delivery. In addition, special glucose transporting molecules have also been developed to assist in cell targeting.

KW - High density lipoproteins

KW - Low density lipoproteins

KW - Lysine residues

KW - Molecular beacons

KW - Nanoparticles

KW - Receptors

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U2 - 10.1007/978-0-387-71809-5_13

DO - 10.1007/978-0-387-71809-5_13

M3 - Conference contribution

AN - SCOPUS:84884994683

SN - 9780387718088

T3 - Lecture Notes in Electrical Engineering

SP - 127

EP - 147

BT - Proceedings of Light-Activated Tissue Regeneration and Therapy Conference

T2 - 2nd Conference on "Light-Activated Tissue Regeneration and Therapy" an Engineering Conference International, ECI 2007

Y2 - 24 June 2007 through 29 June 2007

ER -

Novel targeting and activation strategies for photodynamic therapy

Abstract

Publication series

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Keywords

ASJC Scopus subject areas

Access to Document

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