Nondestructive analysis of mitral valve collagen fiber orientation

R. P. Cochran, K. S. Kunzelman, C. J. Chuong, M. S. Sacks, R. C. Eberhart

Research output: Contribution to journalConference articlepeer-review

59 Scopus citations


Collagen is the most abundant and highest modulus component in mitral valve (MV) tissue. MV leaflet and chordal collagen ultrastructure were analyzed by small angle light scattering (SALS) and polarized light microscopy (PLM) to provide collagen fiber architecture mapping. It was hypothesized that structural arrangement strongly influences MV tissue mechanical properties and thus physiologic function.

Original languageEnglish (US)
Pages (from-to)M447-M448
JournalASAIO Transactions
Issue number3
StatePublished - Jul 1991

ASJC Scopus subject areas

  • Biophysics


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