New Insights into Oncogenic Transformation: Elevating Antioxidant and Nucleotide Levels Does the Trick

Rushendhiran Kesavan, Halie Rion, Gerta Hoxhaj

Research output: Contribution to journalShort surveypeer-review

Abstract

The molecular elements that govern cellular transformation and tumorigenic competence remain poorly understood. Metabolic reprogramming has emerged as a hallmark of malignant transformation. Recently in Cell Metabolism, Zhang et al. showed that an increase of cellular antioxidant capacity and nucleotide availability is sufficient to induce oncogenic transformation and tumorigenesis.

Original languageEnglish (US)
Pages (from-to)177-179
Number of pages3
JournalTrends in Cancer
Volume7
Issue number3
DOIs
StatePublished - Mar 2021

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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