New fluorescent tools for watching nanometer-scale conformational changes of single molecules

Erdal Toprak; Paul R. Selvin

doi:10.1146/annurev.biophys.36.040306.132700

New fluorescent tools for watching nanometer-scale conformational changes of single molecules

Erdal Toprak, Paul R. Selvin

Research output: Contribution to journal › Review article › peer-review

67 Scopus citations

Abstract

Single-molecule biophysics has been serving biology for more than two decades. Fluorescence microscopy is one of the most commonly used tools to identify molecules of interest and to visualize biological events. Here we describe some of the most commonly used fluorescence imaging tools to measure nanoscale movements and the rotational dynamics of biomolecules.

Original language	English (US)
Pages (from-to)	349-369
Number of pages	21
Journal	Annual Review of Biophysics and Biomolecular Structure
Volume	36
DOIs	https://doi.org/10.1146/annurev.biophys.36.040306.132700
State	Published - 2007

Keywords

Fluorescence microscopy
Measuring step sizes
Motility mechanism
Motor proteins

ASJC Scopus subject areas

Biophysics
Structural Biology

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10.1146/annurev.biophys.36.040306.132700

Cite this

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abstract = "Single-molecule biophysics has been serving biology for more than two decades. Fluorescence microscopy is one of the most commonly used tools to identify molecules of interest and to visualize biological events. Here we describe some of the most commonly used fluorescence imaging tools to measure nanoscale movements and the rotational dynamics of biomolecules.",

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AB - Single-molecule biophysics has been serving biology for more than two decades. Fluorescence microscopy is one of the most commonly used tools to identify molecules of interest and to visualize biological events. Here we describe some of the most commonly used fluorescence imaging tools to measure nanoscale movements and the rotational dynamics of biomolecules.

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KW - Measuring step sizes

KW - Motility mechanism

KW - Motor proteins

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DO - 10.1146/annurev.biophys.36.040306.132700

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New fluorescent tools for watching nanometer-scale conformational changes of single molecules

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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