Abstract
Pathological complete response is observed in nearly 20% of patients with rectal cancer receiving preoperative chemoradiation. Patients who achieve a pathological complete response have better outcomes compared to patients experiencing no response or partial response. Current strategies have not demonstrated a substantial improvement in augmenting the ratio of responders to partial and nonresponders. The following discussion addresses possible strategies of investigation to increase patients achieving a complete obliteration of rectal tumors following neoadjuvant chemoradio therapies.
Original language | English (US) |
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Pages (from-to) | 393-396 |
Number of pages | 4 |
Journal | Critical reviews in oncogenesis |
Volume | 17 |
Issue number | 4 |
DOIs | |
State | Published - Dec 5 2012 |
Keywords
- Endorectal ultrasound
- Induction chemotherapy
- Laparoscopic LAR
- Preoperative staging
- Rectum
ASJC Scopus subject areas
- Cancer Research