New clues to actin function in chromatin regulation

Aaron J. Gottschalk, Ronald C. Conaway, Joan Weliky Conaway

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


Since the discovery that actin and actin-related proteins (ARPs) reside in the nucleus as integral subunits of chromatin-modifying and chromatin-remodeling complexes, efforts to uncover their roles in chromatin regulation have met with limited success. In a new study, the previously mysterious helicase-SANT- associated (HSA) domain found in many chromatin regulatory complexes is shown to act as a module that directs recruitment and contributes to the action of actin and ARPs in chromatin regulation.

Original languageEnglish (US)
Pages (from-to)432-433
Number of pages2
JournalNature Structural and Molecular Biology
Issue number5
StatePublished - May 2008
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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