New and emerging renal tumour entities

Naoto Kuroda, Ondřej Hess, Ming Zhou

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


In this review, we discuss new and emerging renal cell carcinoma (RCC) entities, including anaplastic lymphoma kinase (ALK) RCC, oncocytic variant of chromophobe RCC, atrophic kidney-like renal tumour, biphasic alveolosquamoid RCC, tubulocystic RCC, thyroid-like follicular carcinoma of the kidney, succinate dehydrogenase-deficient RCC, Birt-Hogg-Dubé syndrome-associated renal tumour, hereditary leiomyomatosis/renal cell carcinoma associated RCC, tuberous sclerosis-associated RCC, PTEN hamartoma tumour syndrome, clear cell papillary RCC, acquired cystic disease-associated RCC, Xp11.2 RCC, t(6;11) RCC and renal hemangioblastoma. These tumours have clinical, pathological and genetic features distinct from other common RCCs and therefore are important to recognize. Some of them have been recognized as distinct histological subtypes in the 2016 World Health Organization Classification. However, further studies are needed to elucidate their clinicopathologic features and molecular mechanisms.

Original languageEnglish (US)
Pages (from-to)47-56
Number of pages10
JournalDiagnostic Histopathology
Issue number2
StatePublished - Feb 1 2016


  • ALK
  • Acquired cystic disease-associated RCC
  • Anaplastic lymphoma kinase
  • Atrophic kidney-like renal tumour
  • Birt-Hogg-Dubé syndrome-associated renal tumour
  • Clear cell papillary RCC
  • HLRCC associated RCC
  • Succinate dehydrogenase-deficient RCC
  • Thyroid-like follicular carcinoma of the kidney
  • Translocated associated RCC
  • Tuberous sclerosis-associated RCC
  • Tubulocystic RCC

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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