Neuroplasticity and schizophrenia

Douglas O. Frost, Carol A. Tamminga, Deborah R. Medoff, Verne Caviness, Georgio Innocenti, William T. Carpenter

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

This article's title is also the name of a workshop sponsored by the International Congress on Schizophrenia Research that was focused on an appraisal of the potential role of neuroplastic processes in the etiology or course of schizophrenia. The workshop brought together clinical investigators of schizophrenia and basic scientists who study various aspects of neuroplasticity, including central nervous system (CNS) development, learning and memory, and drug action. The goal was to identify special opportunities to advance knowledge and understanding of schizophrenia pathology, treatment, or prevention by applying neuroplasticity concepts as a framework to theories of the illness. Although the focus of this workshop was schizophrenia, the phenomena considered are pertinent to other disorders, such as depression and drug abuse.

Original languageEnglish (US)
Pages (from-to)540-543
Number of pages4
JournalBiological Psychiatry
Volume56
Issue number8
DOIs
StatePublished - Oct 15 2004

Keywords

  • BDNF
  • Schizophrenia
  • course of illness
  • glutamate
  • neurodevelopmental
  • plasticity

ASJC Scopus subject areas

  • Biological Psychiatry

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