Neuronal circuits that regulate feeding behavior and metabolism

Jong Woo Sohn; Joel K. Elmquist; Kevin W. Williams

doi:10.1016/j.tins.2013.05.003

Neuronal circuits that regulate feeding behavior and metabolism

Jong Woo Sohn, Joel K. Elmquist, Kevin W. Williams

Research output: Contribution to journal › Review article › peer-review

187 Scopus citations

Abstract

Neurons within the central nervous system receive humoral and central (neurotransmitter or neuropeptide) signals that ultimately regulate ingestive behavior and metabolism. Recent advances in mouse genetics combined with neuroanatomical and electrophysiological techniques have contributed to a better understanding of these central mechanisms. This review integrates recently defined cellular mechanisms and neural circuits relevant to the regulation of feeding behavior, energy expenditure, and glucose homeostasis by metabolic signals.

Original language	English (US)
Pages (from-to)	504-512
Number of pages	9
Journal	Trends in Neurosciences
Volume	36
Issue number	9
DOIs	https://doi.org/10.1016/j.tins.2013.05.003
State	Published - Sep 2013

Keywords

Agouti-related peptide
Electrophysiology
GABA
Glutamate
Melanocortin receptor
Neuropeptide Y receptor

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.tins.2013.05.003

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title = "Neuronal circuits that regulate feeding behavior and metabolism",

abstract = "Neurons within the central nervous system receive humoral and central (neurotransmitter or neuropeptide) signals that ultimately regulate ingestive behavior and metabolism. Recent advances in mouse genetics combined with neuroanatomical and electrophysiological techniques have contributed to a better understanding of these central mechanisms. This review integrates recently defined cellular mechanisms and neural circuits relevant to the regulation of feeding behavior, energy expenditure, and glucose homeostasis by metabolic signals.",

keywords = "Agouti-related peptide, Electrophysiology, GABA, Glutamate, Melanocortin receptor, Neuropeptide Y receptor",

author = "Sohn, {Jong Woo} and Elmquist, {Joel K.} and Williams, {Kevin W.}",

note = "Funding Information: This work was supported by the American Heart Association (12POST8860007, J.-W.S.) and the National Institutes of Health (P01 DK088761, RL1 DK081185, and R37DK053301, J.K.E.; K01 DK087780, K.W.W.).",

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AU - Sohn, Jong Woo

AU - Elmquist, Joel K.

AU - Williams, Kevin W.

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AB - Neurons within the central nervous system receive humoral and central (neurotransmitter or neuropeptide) signals that ultimately regulate ingestive behavior and metabolism. Recent advances in mouse genetics combined with neuroanatomical and electrophysiological techniques have contributed to a better understanding of these central mechanisms. This review integrates recently defined cellular mechanisms and neural circuits relevant to the regulation of feeding behavior, energy expenditure, and glucose homeostasis by metabolic signals.

KW - Agouti-related peptide

KW - Electrophysiology

KW - GABA

KW - Glutamate

KW - Melanocortin receptor

KW - Neuropeptide Y receptor

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SN - 0378-5912

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JO - Trends in Neurosciences

JF - Trends in Neurosciences

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Neuronal circuits that regulate feeding behavior and metabolism

Abstract

Keywords

ASJC Scopus subject areas

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