Abstract
Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linking the neural circuits regulating energy and glucose balance with current and potential pharmacotherapeutic and surgical interventions for the treatment of obesity and diabetes.
Original language | English (US) |
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Article number | 8054 |
Pages (from-to) | 133-145 |
Number of pages | 13 |
Journal | Cell |
Volume | 161 |
Issue number | 1 |
DOIs | |
State | Published - Mar 26 2015 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology