Nasal Airflow Dynamics following LeFort I Advancement in Cleft Nasal Deformities: A Retrospective Preliminary Study

Daniel Charles, Lucas Harrison, Fatemeh Hassanipour, Rami R. Hallac

Research output: Contribution to journalArticlepeer-review

Abstract

Unilateral cleft lip and palate (UCLP) nasal deformity impacts airflow patterns and pressure distribution, leading to nasal breathing difficulties. This study aims to create an integrated approach using computer-aided design (CAD) and computational fluid dynamics (CFD) to simulate airway function and assess outcomes in nasal deformities associated with unilateral cleft lip and palate (UCLP) after LeFort I osteotomy advancement. Significant alterations were observed in nasal geometry, airflow velocity, pressure dynamics, volumetric flow rate, and nasal resistance postoperatively, indicating improved nasal airflow. The cross-sectional area increased by 26.6%, airflow rate by 6.53%, and nasal resistance decreased by 6.23%. The study offers quantitative insights into the functional impacts of such surgical interventions, contributing to a deeper understanding of UCLP nasal deformity treatment and providing objective metrics for assessing surgical outcome.

Original languageEnglish (US)
Article number1294
JournalDiagnostics
Volume14
Issue number12
DOIs
StatePublished - Jun 2024

Keywords

  • LeFort I advancement
  • cleft lip
  • computational fluid dynamics

ASJC Scopus subject areas

  • Clinical Biochemistry

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